I am a PhD student of the Consciousness and Cognition Lab, investigating the real-world impact of Sleep Disturbance. My primary focus is assessing how Obstructive Sleep Apnoea (OSA) affects driving through a multi-dimensional assessment protocol using portable EEG devices, Temporal Experience Traces, and real-world driving performance measures simultaneously.
I use a pragmatic observational approach to collect large quantities of real-world naturalistic data during the earliest stages of referral to secondary care sleep clinics and throughout patients’ diagnostic treatment pathways. This facilitates ethical monitoring of the impact untreated sleep conditions have without delaying care, as well as enabling assessment of how compliance to therapy improves real world outcomes.
A related focus is identifying factors either behavioural, neurological, or demographic which are related to susceptibility or resilience to condition-induced excessive daytime drowsiness. With the goal to identify potentially modifiable characteristics which can help patients become more receptive to therapy, or not require it at all.
My data is being acquired at the Respiratory Support and Sleep Centre, Royal Papworth Hospital, Biomedical Campus, Cambridge.
The work is being delivered under the joint supervision of the Royal Papworth Hospitals Director of Medicine, Dr Ian Smith and the Consciousness and Cognition Lab PI, Associate Professor Tristan Bekinschtein.
Key Research Papers
- Andrienko, G., Andrienko, N., Kureshi, I., Lee, K., Smith, I., & Staykova, T. (2021). Automating and utilizing equal-disruption data classification, International Journal of Cartography, 7(1).
- Lee, K., Carter, V., Skinner, D., Beech, K., Chalmers, J., Clark., A., Halpin, D., Hannan, N., Kaplan, A., Kostikas, K., Pinnock, H., Roche, N., Usmani, O., Van Boven, J., Mastoridis, P., Jones, R., & Price, D. (2021). Poor adherence in exacerbating COPD patients: magnitude and related factors at baseline in the MAGNIFY pragmatic trial, Abstract from PCRS Respiratory Conference 2021.
- Lee, K., Andrienko, N., Andrienko, G., Kureshi, I., Staykova, T., & Smith, I. (2021). Social deprivation appears to be a barrier to referral for investigation of obstructive sleep apnoea, Thorax 2021, 76, A77.
- Qian, M., Lee, K., Palas, E., George, S., Huang, Y., Rahman, S., Li, N., Wong, D., Mason, M., & Smith, I. (2020). Does chronic opioid use impact OSA diagnosis and response to treatment with CPAP?, European Respiratory Journal 2020, 56, 2152.
- Lee, K., Mason, M., & Smith, I. (2019). Obstructive sleep apnoea (OSA) severity in patients with chronic opioid use: a risk factor matched study, Thorax, 74, A188.
- Lee, K., Andrienko, N., Andrienko, G., Kureshi, I., Staykova, T., & Smith, I. (2019). Aggregated Patient Journeys and no-show rates of Oximetry Outreach Network in East Anglia, BMJ Open Respiratory Research, 6 (suppl 1), A27.
- Lee, K., & Smith, I. (2019). GP based oximetry as an initial diagnostic test for Obstructive Sleep Apnoea (OSA), outcomes, BMJ Open Respiratory Research, 6 (suppl 1), A28.
- Lee, K., Mason, M., & Smith, I. (2018). Obstructive Sleep Apnoea (OSA) and response to CPAP treatment in patients with chronic Opioid use, Thorax, 73 (suppl 4), A128 – A129.